Serum proteins profile in Comisana lambs during the first month of life

The aim of the present study was to measure the serum total proteins and the serum protein fractions (albumin, α1-, α2-, βand γ-globulins) of ten newborn lambs (Comisana breed) during the first 30 days of life in order to obtain useful information for neonatal care. From each animal, blood samples were collected via jugular venepuncture at the same hour (9.00) every 3 days for 30 days starting from birth (day 0). The concentrations of serum total proteins and albumin, α1-, α2-, β-, γglobulins and albumin/globulins ratio were determined using an automated electrophoresis system. One-way repeated measures analysis of variance (ANOVA) followed by Bonferroni test was used to determine significant differences between mean values of the studied parameters from the 1st to the 30th day of the experimental period. Data analysis of variance showed a statistical effect of days of life on total proteins, albumin, α1-globulins, β-globulins, γ-globulins and albumin/globulins ratio during the first 30 days of life (P<0.0001), while no statistical significant effect of days of life was observed on α2-globulins during the experimental period (P=0.27). The obtained results indicated that passive transfer status, determined from serum immunoglobulin concentration 24 h after birth, is a significant source of variation in pre-weaning growth performance in dairy lambs. These finding make a contribution to the knowledge of physiological adaptation in lambs during the first 30 days of life and give useful information for the diagnosis and treatment of neonatal diseases.